WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: .05, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Tight junction 10 154810 50855 29119 22808 7082 88 9223 22800 51776 10627 C=132;O=10;E=0.88;R=11.34;rawP=2.30e-08;adjP=1.43e-06
Regulation of actin cytoskeleton 10 2246 10152 9459 22808 55740 88 7414 22800 10627 1073 C=213;O=10;E=1.42;R=7.03;rawP=1.96e-06;adjP=4.61e-05
MAPK signaling pathway 11 2246 2318 6722 22808 8491 6885 22800 51776 781 5567 51347 C=268;O=11;E=1.79;R=6.15;rawP=2.23e-06;adjP=4.61e-05
Adherens junction 6 7082 88 10580 6885 29119 7414 C=73;O=6;E=0.49;R=12.31;rawP=9.85e-06;adjP=0.0002
Focal adhesion 8 2318 595 2932 596 88 7414 10627 858 C=200;O=8;E=1.34;R=5.99;rawP=6.54e-05;adjP=0.0008
Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5 88 29119 1756 1000 781 C=74;O=5;E=0.49;R=10.12;rawP=0.0001;adjP=0.0010
Neurotrophin signaling pathway 6 2932 10971 596 57498 2549 5781 C=127;O=6;E=0.85;R=7.07;rawP=0.0002;adjP=0.0018
Insulin signaling pathway 6 5563 2932 10580 10891 1978 5567 C=138;O=6;E=0.92;R=6.51;rawP=0.0003;adjP=0.0023
Leukocyte transendothelial migration 5 88 29119 7414 10627 5781 C=116;O=5;E=0.77;R=6.45;rawP=0.0011;adjP=0.0068
Adipocytokine signaling pathway 4 5563 3717 10891 5781 C=68;O=4;E=0.45;R=8.81;rawP=0.0011;adjP=0.0068
Bacterial invasion of epithelial cells 4 29119 7414 858 2549 C=70;O=4;E=0.47;R=8.56;rawP=0.0013;adjP=0.0073
Hypertrophic cardiomyopathy (HCM) 4 5563 7273 1756 781 C=83;O=4;E=0.55;R=7.22;rawP=0.0024;adjP=0.0124
Prostate cancer 4 2932 595 596 9586 C=89;O=4;E=0.59;R=6.73;rawP=0.0030;adjP=0.0132
Dilated cardiomyopathy 4 7273 1756 781 5567 C=90;O=4;E=0.60;R=6.66;rawP=0.0032;adjP=0.0132
ErbB signaling pathway 4 2932 1839 2549 1978 C=87;O=4;E=0.58;R=6.88;rawP=0.0028;adjP=0.0132
mTOR signaling pathway 3 5563 253260 1978 C=52;O=3;E=0.35;R=8.64;rawP=0.0051;adjP=0.0186
Endometrial cancer 3 2932 595 29119 C=52;O=3;E=0.35;R=8.64;rawP=0.0051;adjP=0.0186
Inositol phosphate metabolism 3 8871 8821 51196 C=57;O=3;E=0.38;R=7.88;rawP=0.0066;adjP=0.0227
Colorectal cancer 3 2932 595 596 C=62;O=3;E=0.41;R=7.25;rawP=0.0083;adjP=0.0271
Cell cycle 4 2932 10971 595 7465 C=124;O=4;E=0.83;R=4.83;rawP=0.0098;adjP=0.0304
Epithelial cell signaling in Helicobacter pylori infection 3 7082 1839 5781 C=68;O=3;E=0.45;R=6.61;rawP=0.0107;adjP=0.0316
Axon guidance 4 2932 10512 1073 10509 C=129;O=4;E=0.86;R=4.64;rawP=0.0112;adjP=0.0316
Phosphatidylinositol signaling system 3 8871 8821 51196 C=78;O=3;E=0.52;R=5.76;rawP=0.0155;adjP=0.0418
Wnt signaling pathway 4 2932 595 6885 5567 C=150;O=4;E=1.00;R=3.99;rawP=0.0185;adjP=0.0478


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).